Couple neat programs I heard about the other day.
Essentially they let you scroll your mouse wheel in programs without actually having the windows be in focus (plus a few other options). Extremely useful in multiple monitor setups.
WizMouse (my favorite)
http://antibody-software.com/web/software/software/wizmouse-makes-your-mouse-wheel-work-on-the-window-under-the-mouse/
KatMouse
http://ehiti.de/katmouse/